Laurens J. Mets

Associate Professor
Research Summary
Current research interest: What can we do to reduce the environmental and geopolitical risks engendered by current practices in the use by humans of non-food energy to support life and society? Criteria for such a future energy system: 1) It should tap into natural energy fluxes rather than exploiting static resources. The energy fluxes must be so large that the portion needed for human uses is a very small fraction that does not disturb the natural order. Energy fluxes that generally meet this criterion: solar (and its derivatives wind, hydro); geologic (geothermal, gravitational & tidal); nuclear. 2) Energy capture and use should not require crossing geopolitical boundaries for either the energy sources or the materials required to support capture and use. 3) Given the current investment in energy transport, storage and use infrastructure, rapid conversion to reliance on only these primary energy resources requires similar end-use forms of energy and energy carriers (electric power, natural gas, liquid fuels). Relatively mature methods exist for converting solar, wind and nuclear resources to electric power. My research focuses on enabling these resources to also supply the balance of society's energy needs by producing fuels (renewable natural gas and liquid fuels) from waste carbon dioxide and market-excess (spatially or temporally stranded or otherwise curtailed) solar, wind or nuclear power.
Education
  • Pomona College, Claremont, CA, BA Chemical Biology 06/1968
  • Harvard University, Cambridge, MA, MA, PhD Biological Chemistry 06/1972
Biosciences Graduate Program Association
Publications
  1. Fu Y, Luo GZ, Chen K, Deng X, Yu M, Han D, Hao Z, Liu J, Lu X, Dore LC, Weng X, Ji Q, Mets L, He C. N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas. Cell. 2015 May 07; 161(4):879-892. View in: PubMed

  2. Monson RK, Teeri JA, Ku MS, Gurevitch J, Mets LJ, Dudley S. Carbon-isotope discrimination by leaves of Flaveria species exhibiting different amounts of C3-and C 4-cycle co-function. Planta. 1988 May; 174(2):145-51. View in: PubMed

  3. Martin MR, Fornero JJ, Stark R, Mets L, Angenent LT. A single-culture bioprocess of Methanothermobacter thermautotrophicus to upgrade digester biogas by CO2 -to-CH4 conversion with H2. Archaea. 2013; 2013:157529. View in: PubMed

  4. Strack RL, Strongin DE, Mets L, Glick BS, Keenan RJ. Chromophore formation in DsRed occurs by a branched pathway. J Am Chem Soc. 2010 Jun 23; 132(24):8496-505. View in: PubMed

  5. Hohmann-Marriott MF, Takizawa K, Eaton-Rye JJ, Mets L, Minagawa J. The redox state of the plastoquinone pool directly modulates minimum chlorophyll fluorescence yield in Chlamydomonas reinhardtii. FEBS Lett. 2010 Mar 05; 584(5):1021-6. View in: PubMed

  6. Merchant SS, Prochnik SE, Vallon O, Harris EH, Karpowicz SJ, Witman GB, Terry A, Salamov A, Fritz-Laylin LK, Maréchal-Drouard L, Marshall WF, Qu LH, Nelson DR, Sanderfoot AA, Spalding MH, Kapitonov VV, Ren Q, Ferris P, Lindquist E, Shapiro H, Lucas SM, Grimwood J, Schmutz J, Cardol P, Cerutti H, Chanfreau G, Chen CL, Cognat V, Croft MT, Dent R, Dutcher S, Fernández E, Fukuzawa H, González-Ballester D, González-Halphen D, Hallmann A, Hanikenne M, Hippler M, Inwood W, Jabbari K, Kalanon M, Kuras R, Lefebvre PA, Lemaire SD, Lobanov AV, Lohr M, Manuell A, Meier I, Mets L, Mittag M, Mittelmeier T, Moroney JV, Moseley J, Napoli C, Nedelcu AM, Niyogi K, Novoselov SV, Paulsen IT, Pazour G, Purton S, Ral JP, Riaño-Pachón DM, Riekhof W, Rymarquis L, Schroda M, Stern D, Umen J, Willows R, Wilson N, Zimmer SL, Allmer J, Balk J, Bisova K, Chen CJ, Elias M, Gendler K, Hauser C, Lamb MR, Ledford H, Long JC, Minagawa J, Page MD, Pan J, Pootakham W, Roje S, Rose A, Stahlberg E, Terauchi AM, Yang P, Ball S, Bowler C, Dieckmann CL, Gladyshev VN, Green P, Jorgensen R, Mayfield S, Mueller-Roeber B, Rajamani S, Sayre RT, Brokstein P, Dubchak I, Goodstein D, Hornick L, Huang YW, Jhaveri J, Luo Y, Martínez D, Ngau WC, Otillar B, Poliakov A, Porter A, Szajkowski L, Werner G, Zhou K, Grigoriev IV, Rokhsar DS, Grossman AR. The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science. 2007 Oct 12; 318(5848):245-50. View in: PubMed

  7. Tong L, Mets L, McPeek MS. Likelihood-based inference for multi-color optical mapping. Stat Appl Genet Mol Biol. 2007; 6:Article5. View in: PubMed

  8. Mets LJ, Geist LJ. Linkage of a Known Chloroplast Gene Mutation to the Uniparental Genome of CHLAMYDOMONAS REINHARDII. Genetics. 1983 Nov; 105(3):559-79. View in: PubMed

  9. Galloway RE, Mets LJ. Atrazine, bromacil, and diuron resistance in chlamydomonas: a single non-mendelian genetic locus controls the structure of the thylakoid binding site. Plant Physiol. 1984 Mar; 74(3):469-74. View in: PubMed

  10. Qu X, Wu D, Mets L, Scherer NF. Nanometer-localized multiple single-molecule fluorescence microscopy. Proc Natl Acad Sci U S A. 2004 Aug 03; 101(31):11298-303. View in: PubMed

  11. Lee JW, Mets L, Greenbau E. Improvement of photosynthetic CO2 fixation at high light intensity through reduction of chlorophyll antenna size. Appl Biochem Biotechnol. 2002; 98-100:37-48. View in: PubMed

  12. Shu G, Pontieri V, Dengler NG, Mets LJ. Light induction of cell type differentiation and cell-type-specific gene expression in cotyledons of a C(4) plant, Flaveria trinervia. Plant Physiol. 1999 Nov; 121(3):731-41. View in: PubMed

  13. Mets LJ, Bogorad L. Mendelian and uniparental alterations in erythromycin binding by plastid ribosomes. Science. 1971 Nov 12; 174(4010):707-9. View in: PubMed

  14. Mets LJ, Bogorad L. Two-dimensional polyacrylamide gel electrophoresis: an improved method for ribosomal proteins. Anal Biochem. 1974 Jan; 57(1):200-10. View in: PubMed

  15. Bogorad L, Mets LJ, Mullinix KP, Smith HJ, Strain GC. Possibilities for intracellular integration: The ribonucleic acid polymerases of chloroplasts and nuclei, and genes specifying chloroplast ribosomal proteins. Biochem Soc Symp. 1973; (38):17-41. View in: PubMed

  16. Hanson MR, Davidson JN, Mets LJ, Bogorad L. Characterization of chloroplast and cytoplasmic ribosomal proteins of Chlamydomonas reinhardi by two-dimensional gel electrophoresis. Mol Gen Genet. 1974; 132(2):105-18. View in: PubMed

  17. Martineau B, Smith HJ, Dean C, Dunsmuir P, Bedbrook J, Mets LJ. Expression of a C3 plant Rubisco SSU gene in regenerated C4 Flaveria plants. Plant Mol Biol. 1989 Oct; 13(4):419-26. View in: PubMed